| 목록구분 | 소장기록 |
|---|---|
| 식별번호 | F-BC-0032 |
| 표제 | Sources of polycyclic aromatic hydrocarbon exposure in non-occupationally exposed Koreans 2003 |
| 내용 | Urinary 1-hydroxypyrene (1-OHP), an exposure biomarker for polycyclic aromatic hydrocarbons (PAHs), was used to identify potential sources of PAH exposure for 660 Koreans who were not occupationally exposed to PAHs (65% male; 35% female; mean age, 36.5 ± 11.1 years). In this study, 74% of subjects had detectable levels of urinary 1-OHP, with a concentration range of 0.001–3.796 μg/L (median, 0.079 μg/L). A backward elimination was conducted: five variables were selected with a significance level for removal of P ≤ 0.1. The results of this study showed that residence in areas with relatively poor environmental conditions (Seoul and Suwon) was strongly associated with high concentrations of urinary 1-OHP (P = 0.007), while consumption of fried chicken and length of time spent outdoors had marginal positive associations with urinary 1-OHP levels (P = 0.06 and P = 0.09, respectively). Compared with the above three factors, tobacco smoking and urinary cotinine levels were poorly associated with urinary 1-OHP (P = 0.16 and 0.23, respectively). Pear consumption had an inverse association with urinary 1-OHP levels (P < 0.01). Individual variations in urinary 1-OHP concentrations were evaluated by considering the subjects' age, sex, and genetic polymorphisms in enzymes involved in the metabolism of PAHs. Among the individual variations, GSTT1-present subjects showed higher 1-OHP levels than GSTT1-absent subjects in cities having 10-μm particulate matter (PM10) levels and population density lower than those of Seoul and Suwon (P < 0.05). These epidemiological results suggest that the above factors that should be considered in preventing PAH exposure. Environ. Mol. Mutagen. 42:250–257, 2003. © 2003 Wiley-Liss, Inc. https://blog.naver.com/free5293/220425279917 ※ 저작권 관련으로 원문은 서비스 되지 않습니다. |
| 기록물유형 | 문서류 |
| 기록물형태 | 논문 |
| 생산자 | Mihi Yang; Soyeon Kim; Eunil Lee; Hae-Kwan Cheong; Seong-Sil Chang; Daehee Kang; Yunhee Choi; Su-Man Lee; Jae-Yeon Jang |
| 생산일자 | 2003-11-00 |
| 키워드 | |
| 원본형태 | 전자 |
| 크기분량 | 100KB; 8쪽 |
| 언어 | 영어 |
| 관리번호 | 49963 |