| 목록구분 | 소장기록 |
|---|---|
| 식별번호 | F-BC-0024 |
| 표제 | Application of biological monitoring to the quantitative exposure assessment for neuropsychological effect 1999 |
| 내용 | International Archives of Occupational and Environmental Health March 1999, Volume 72, Issue 2, pp 107-114 Application of biological monitoring to the quantitative exposure assessment for neuropsychological effect by chronic exposure to organic solvents Jae-Yeon Jang, Soon Young Lee, Jae Ill Kim, Jae Beom Park, Kyung Jong Lee, Ho Keun Chung Abstract Objective: Quantitative exposure assessment became more common as a result of attempts to reduce nondifferential exposure misclassification and to observe a steeper exposure-response relationship. Several exposure variables were compared in a demonstration of the exposure-response relationship between neuropsychological abnormality and long-term exposure to organic solvents in workers at one shipyard. Method: Environmental monitoring and biological monitoring were performed to evaluate the exposure of the workers to organic solvents. Cumulative exposure (CE) and lifetime-weighted average exposure variables were developed with both environmental and biological monitoring data. A neuropsychological questionnaire and a function test for confirmation of a disorder or dysfunction in attention, executive function, visuospatial, and constructional abilities, learning and memory, and psychomotor function were performed. Results: The abnormal rate in neuropsychological diagnosis was 9.3% in the exposed group, which was much higher than the 2.1% rate obtained in the nonexposed group (P < 0.01). The neuropsychological abnormal rate showed a significant dose-response association with CE created with biological monitoring data. The results also suggest that biological monitoring can provide impressive and effective information for quantitative exposure assessment, even in epidemiology studies. Received: 2 April 1998 / Accepted: 23 September 1998 https://blog.naver.com/free5293/220425254161 ※ 저작권 관련으로 원문은 서비스 되지 않습니다. |
| 기록물유형 | 문서류 |
| 기록물형태 | 논문 |
| 원본소장처 | International Archives of Occupational and Environmental Health |
| 생산자 | Jae-Yeon Jang; Soon Young Lee,; Jae Ill Kim; Jae Beom Park; Kyung Jong Lee; Ho Keun Chung |
| 생산일자 | 1999-03-00 |
| 키워드 | |
| 원본형태 | 전자 |
| 크기분량 | 101KB; 8쪽 |
| 언어 | 영어 |
| 관리번호 | 49955 |